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| All special moves | 100% | |
| Have the Game Boy Advance game Spider-Man: Mysterio's Menace in the cartridge slot to unlock the all special moves. | ||
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| Unlimited special meter | 100% | |
| Get a 100% game completion to unlock an unlimited special meter. | ||
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| Chapter 9: Special move upgrade | 100% | |
| The upgrade is located very high above the movie theater. To reach it, super jump from a high ledge and swing around until you see it. Hint: Chapter 11: Special move upgrade: Keep going right though the level until you reach the train station, over the electric trap. Keep swinging while holding up Left and Right until you reach the hidden power-up. | ||
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| Glitch: Invisible Mysterio | 100% | |
| When Mysterio divides, keep shooting until you hit the real Mysterio. Now, quickly tap Y. He will be invisible at the same location where he always ends up. He will remain this way for the rest of the game -- beat him up hard. | ||
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| Chapter 7: Special move upgrade | 100% | |
| When you start the chapter, move to the left and get to the top of the building that is farthest to the left. Super jump, then web sling to the right at the top of your jump. Avoid the helicopter and collect the upgrade. | ||
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| All special moves | 98% | |
| Have the Game Boy Advance game Spider-Man: Mysterio's Menace in the cartridge slot to unlock the all special moves. | ||
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| Take Doc Ock out faster | 98% | |
| Here Is how you take Doc Ock out. You need to make sure that you have the ball combo or item then keep using it. When you have one left jump for a item and switch it tell you have a refill. You need to make sure you have a lot of health so you don't die. | ||
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| Chapter 3: Special move upgrade | 98% | |
| Continue to the right until you reach a train station. Now, look under the electric trap. | ||
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| Faster recharging special meter | 98% | |
| Win the game (Chapter 14) once to receive a faster recharging special meter. | ||
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| Defeating Doc Ock | 98% | |
| Your Spidey Sense will trigger just before Doc Ock fully extends his tentacles forward to hit you. When this happens, enter slow motion, jump over the tentacles, and land next to Doc Ock. His tentacles will be unable to reach you for a few seconds. Use this time to attack him, them jump out of the way. Shoot impact web from a safe distance until the tentacles extend again, then repeat the tactic. | ||
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| Defeating Doc Ock's robots | 98% | |
| Web Zip to a wall while an enemy is in your way. This will destroy them with one shot. Another easy way to destroy them is to hit them 3 times with Impact Web. | ||
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| Spiderman2 | 100% | |
| When your faceing mysterio always use the web balls. | ||
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| To full health | 63% | |
| R,x,x,y,a,b,b,,y,y,x,b,a | ||
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Based on this summer’s blockbuster feature film from Columbia Pictures and Marvel, Spider-Man 2™ for the Nintendo DS leverages the new system’s processing power and dual-screens to deliver an entirely new gameplay experience. Players assume the role of the most celebrated super-hero of all time and re-live the movie experience through all new missions featuring unique enemies, objectives and combat maneuvers. Utilizing the touch screen and new controller layout, players can quickly swing, run, jump, solve puzzles, engage in combat and switch to an arsenal of moves on the fly, while patrolling and protecting the city of Manhattan from the nefarious Doc Ock.