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| Hopper 7 mode | 100% | |
| Win the game in Killer 8 mode. Alternate ending sequence: Complete Killer 8 mode. | ||
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| 100 vials of serum | 100% | |
| At the press start screen, enter DOWN, R, UP, L, Y, B, X, A | ||
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| Codes | 100% | |
| Infinite Vials of Serum for killer 8 mode Enter this code at the press start screen. You will get 100 free vials of serum each time that you start the 1st level. By begining the 1st level repeatedly, you will recieve 100 free vials each time giving you an infinite amount. This will only work in Killer 8 mode only.CodeEffect Down, R, Up, L, Y, B, X, A100 vials of serum | ||
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| Thick Blood & Serum | 100% | |
| Thick blood is not carried over from stage to stage, but serum is. The blood machine in each stage will cease to function if you revisit the stage, so learn to collect as much thick blood as possible in a stage and break the machine before moving on. | ||
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| Unlockables | 100% | |
| Extra game modes UnlockableHow to Unlock Hopper 7 modeComplete Killer 8 mode Killer 8 hard modeComplete full game on normal or hard mode Playable character: Young HarmanComplete full game on normal or hard mode | ||
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| Unlock Hopper 7 | 100% | |
| Unlock Hopper 7 mode by clearing Killer 8 mode. Hopper 7 only plays through the first stage. | ||
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| Unlock Killer 8 | 100% | |
| Clear the game and unlock Killer 8 mode, where the changes include: Enemy critical spots are invisible Enemy explosions do five times normal damage Clue and map icons are hidden on the map menu | ||
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| Killer 8 mode | 100% | |
| Win the game under the normal or hard difficulty setting. Young Harman is a playable character in this mode. | ||
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