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| Big head mode | 100% | |
| At the "Press Start" screen, press X, B, Up, Down. | ||
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| Flat mode | 100% | |
| At the "Press Start" screen, press Down, Up, B, X. | ||
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| Small head mode | 100% | |
| At the "Press Start" screen, press X, B, Down, Up. | ||
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| Iron Mike | 100% | |
| Win the Mike Tyson challenge to unlock Iron Mike, the early version of Mike Tyson. | ||
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| All boxers | 100% | |
| Win the Bronze, Silver, and Gold belts to unlock all boxers including Mike Tyson. | ||
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| Mike Tyson challenge | 100% | |
| Defeat Mike Tyson and win the Gold belt to unlock the undisputed champ mode. | ||
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