Based on a true story involving a cult in the mountains of Japan, Fatal Frame takes place in the haunted Himuro mansion and nearby surrounding area.

The story revolves around the main character Miku, who is searching for her brother, who has been missing for two weeks. He disappeared while searching for his mentor, who was last seen entering the mansion. Miku is gifted with the ability to foresee events that took place in the past or future. When she finds a photograph of a victim with rope marks on his wrists, just by touching the photo, she experiences a flashback of how that person received those rope marks. Feeling somewhat uneasy about her brother’s disappearance, Miku decides to go to the mansion looking for him, not knowing what awaits her there…